In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum replacement to effectively culture functional monocyte-derived dendritic cells and macrophages.

Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that interact with endothelial cells under physiological or pathophysiological conditions to orchestrate ...

We evaluated cell death of primary human endothelial and nasal epithelial cells, and blood-isolated monocytes, neutrophils and lymphocytes. Portimine A induced cell death only in endothelial and nasal ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Basal-like breast cancers exhibit distinct ...

Centre for Inflammation Research, The University of Edinburgh, Edinburgh EH16 4UU, U.K. IRR Chemistry Hub, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, U.K.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. High-throughput measurement of cellular traction forces at the nanoscale remains a ...

Surprisingly, we observed that recombinant SARS-CoV-2 Spike (S) and Nucleocapsid (N) proteins triggered only a weak proinflammatory response in human peripheral blood monocytes. By employing THP-1 and ...

By utilizing quantitative and qualitative models, we discovered that soluble factors secreted by human monocytes potently inhibit SARS-CoV-2-induced cell-cell fusion in viral-infected cells. Through ...