Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.
Hu, C. Yau and A. Ahmed (2017 ... While some mutations can introduce premature termination codons (PTCs) into genes, nonsense mediated decay (NMD) can detect these PTCs and then eliminate the abnormal ...
Forest parks suffer ‘extensive’ damage as NMD Council work on providing for vulnerable residents
The past number of days have brought unprecedented challenges as Storm Éowyn swept through Co Armagh, leaving a profound impact on communities and a trail of destruction and disruption. As a result, ...
As Donald Trump takes his oath of office to become the 47th President of the United States and begin his second tenure, politicians, the Trump clan, tech titans et al have arrived at the US ...
Nonsense-mediated mRNA decay (NMD) largely provides a means to ensure the quality of gene expression by eliminating mRNAs that prematurely terminate translation either because of genomic mutations ...
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