New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...

New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of ...

Researchers are investigating whether a common cholesterol drug could be repurposed to treat HPV-positive cervical cancer.

Researchers sought to evaluate differences in ctDNA profiles, use of targeted treatments, and overall survival between Black and White patients with metastatic breast cancer.

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Although there are tumor suppressor genes in normal cells to prevent cancer, gene mutations can cause a normal cell to become ...

Mutations in the TP53 gene occur in approximately half of human cancer types ... described the effect of rezatapopt (PC-14586), a first-in-class selective p53 reactivator designed to reinstate p53 ...