For instance, bacteria contain a single type of RNA polymerase, while eukaryotes (multicellular organisms and yeasts) contain three distinct types. In spite of these differences, there are ...

In eukaryotes, DNA is tightly wound into a complex ... in turn, recruit RNA polymerase II (Turner, 2005). Varying levels and types of histone modifications have been shown to correlate with ...

We focus on transcription by RNA polymerase II (Pol II), the enzyme that is responsible for transcribing all protein-encoding genes in eukaryotes. Many diseases including cancer are caused by defects ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Eukaryotic cells respond to these challenges by activating ... Ccr4-Not travels with elongating RNA polymerase II (RNAPII) to prevent arrest, and we recently have shown it is involved in the ...

Pavesi A, Conterio F, Bolchi A, Dieci G, Ottonello S (1994). Identification of new eukaryotic tRNA genes in genomic DNA databases by a multistep weight matrix analysis of transcriptional control ...