Nucleoside analogs are transformative in cancer and antiviral therapies, offering new avenues for treatment despite ...

Among the findings, the Japanese contributors detected all five nitrogenous bases, molecules required for building DNA and RNA, supporting the theory ... the ratio of purines (adenine and guanine) to ...

Antimetabolites. These include 5-fluorouracil, which is a fluoropyrimidine analogue of the endogenous pyrimidine nucleoside that perturbs RNA and DNA synthesis. Gemcitabine (Gemzar; Eli Lilly ...

By Sage Rohrbach A mosaic image of the Bennu Asteriod, created using pictures from NASA’s OSIRIS-REx satellite that was near the asteroid for over two years. Courtesy of NASA via Wikimedia ...

Thus the inhibition of DHODH by A77 1726 prevents lymphocytes from accumulating sufficient pyrimidines to support DNA synthesis. At higher doses, A77 1726 inhibits tyrosine kinases responsible for ...

This should be taken into account, when interpreting the results. The ROS/RNS react with DNA inducing damage to purine and pyrimidine bases and also the deoxyribose backbone (Halliwell, 2000).

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a devastating ...

CFO Beth Jantzen reported total revenues of $1.2 million for Q1 2025, a year-over-year increase driven by higher product revenue from DNA Tagging and increased isotopic testing services. Operating ...

Ancient DNA analysis provides new insights into our linguistic roots. Where did the Indo-European language family originate?

Stanford scientists have identified 380 key genetic variants that significantly influence cancer development, filtering ...