We are in the midst of an RNA revolution, set to change the future of medicine. However, that revolution is now in jeopardy. The Yeo lab focuses on the function and therapeutic applications of RNA, a ...

There are, of course, the standard prokaryotic, yeast and mammalian leagues. Within the last few years, a number of expansion leagues have been added, including Baculovirus and specialized spin-offs ...

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

Unlike the nuclear genome, most eukaryotes pack their circular mtDNA into nucleoids ... You could conceivably retrieve all of your barcode sequences in a single NGS run,” said Liu. RNA sequencing (RNA ...

ProkSeq is a docker based, full RNA-Seq pipeline for prokaryotes, which includes quality assessment, alignment, gene counting, and analysis. The count tables countFile.csv, countFileNucleotideAvgCount ...

Then, other TFs (lacking the above capability) become able to bind DNA and activate gene transcription by interacting with the RNA polymerase machinery (Farnham ... Generally, in eukaryotes, the ...

We have performed ChIP-seq experiments on tightly staged Drosophila embryos and show that massive recruitment of RNA polymerase II (Pol II) with widespread pausing occurs de novo during the ...