Researchers at Karolinska Institutet and Uppsala University have developed a powerful new technique to better understand how ...

RBP3 as a large molecule consisting of four retinoid-binding modules, has long lost its original catalytic functionality, and it evolved to be a cargo transporter interacting with a variety of ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Artificial Intelligence (AI) tools for language processing are ...

Work by the Birmingham scientists identified two sequences of three amino acids that showed biological activity comparable to the full-length PEPITEM molecule. The scientists then optimised these ...

Division of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China ...

Structure: DNA is composed of two long chains of nucleotides forming a double helix. The nucleotides within each strand are joined together through covalent (specifically phosphodiester) bonds between ...

Finally, quantification of metabolites revealed increasing pyrimidine pools as a late feature of the SOS ... was used to quantify phosphorylated metabolites, organic acids, and intermediates of the ...

However, a major obstacle that still hinders the broader success of nucleic acid-based therapies and vaccines lies in the inefficient delivery of these biopolymers to human cells, as well as in ...