Here, Johannesman et al demonstrate that some phages have co-opted an orphan antitoxin to counter a DNA ADP-ribosyltransferase defense system. Selecting subsets of specific sequences from complex ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

Cancer Biologists Discover a New Mechanism for an Old Drug Oct. 7, 2024 — Doctors have long believed the cancer drug 5-fluorouracil works by damaging the building blocks of DNA, but researchers ...

The table is limited by our hospital pharmacy's formulary; however, our purpose was to update the current literature. The table is intended for use as a guide when medications labeled for ...

Here, the authors developed a cell-based screening assay for the identification of small molecule inhibitors of nonsense-mediated decay (NMD), and used it to validate KVS0001, a new small molecule ...

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