The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

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Intermediate ILC2s share traits of both ILC2s and another type of immune cell called group 3 innate lymphoid cells, or ILC3s. ILC3s are tied to another type of white blood cell called neutrophils. An ...

Cancer immunotherapy has shown significant potential in treating several malignancies by stimulating the host immune system to recognize and attack ... (miRNA, MicroRNA; lncRNA, Long non-coding RNA; ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex ... for both transcription and RNA replication and mutations that have ...

This dysfunction is marked by the upregulation of exhaustion markers like PD-1 and TIM-3, and a reduction in effector memory ... host restriction factors—components of the innate immune system—act to ...

This is where DNA and RNA epigenetics come in: a series of mechanisms that act as "markers" on genes, to control their activity without modifying the DNA or RNA sequence itself. Until now ...