A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during gene expression, findings that may inform the ...

Until now, the structure and function of the Nipah virus polymerase remained poorly understood ... that are required for both transcription and RNA replication and mutations that have a greater ...