RNA Polymerase III (Pol III ... specifically those containing the subunits POLR3G and POLR3GL, can significantly influence transcriptional outcomes and cellular behavior in cancerous tissues.

Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read “snurps ...

Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read “snurps”) – ...

NASA iCOOL (Center for the Integration of the Origins of Life) and School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, United States Institute of ...

Mitochondrial RNA polymerase (POLRMT) is an RNA polymerase that executes the transcription of the mtDNA. In comparison to the POLγA-related neurological diseases, a relatively less neuronal pathology ...

You’ve certainly heard about antibodies, peptides, and even DNA as therapeutics, but what about RNA? In this review, we take a look at what’s happening in a field that some believe may be as big a ...

Aging is an inevitable progressive decline in physiological organ function that increases the chance of disease and death. The renin–angiotensin system (RAS) is involved in the regulation of ...

Graca et al. reports a fundamental missing link in the ethanol metabolism of mycobacteria and illuminates the role of a flavoprotein dehydrogenase that acts as an electron shuttle between an uncommon ...

This valuable work examines the role of the oxidoreductase MftG in Mycolicibacerium smegmatis alcohol metabolism. A solid set of data is presented to show that, in the context of ethanol metabolism, ...

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...