Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...

A study reveals DNA and RNA epigenetics work together as a complementary system for precise gene regulation, crucial for cell ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs, and an intricate frameshift site structure that regulate viral protein synthesis. These findings highlight ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

The findings demonstrate that, under certain circumstances, the RNA polymerase (RNAP ... so cells have many redundant mechanisms to prevent them from forming," says Seth Darst, head of the ...

Researchers at the Medical University of South Carolina have discovered a key genetic mechanism that could lead to RNA-based therapies for psychiatric disorders triggered by emotional experiences.

CREATE operates entirely through RNA components without requiring DNA donor templates or double-strand breaks. CREATE incorporates multiple built-in checkpoint mechanisms to ensure precise on-target ...