it is first necessary to examine the mechanisms of RNA transcription in more detail. In bacteria, all transcription is performed by a single type of RNA polymerase. This polymerase contains four ...

"When SPT5 is lost, this ARMC5 mechanism will recognize RNA polymerase II and then eliminate this defective transcription complex." The findings may also inform the understanding of the ...

Trends Biochem Sci 2022, 47: 314 - 327. Palacio, M; Taatjes DJ. Merging established mechanisms with new insights: Condensates, hubs, and the regulation of RNA polymerase II transcription. J Mol Biol ...

Trends Biochem Sci 2022, 47: 314 - 327. Palacio, M; Taatjes DJ. Merging established mechanisms with new insights: Condensates, hubs, and the regulation of RNA polymerase II transcription. J Mol Biol ...

Researchers have identified cellular factors that regulate the delivery and stability of mRNA to expand the potential of mRNA ...

This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions ... RNA interference (RNAi) is a cellular mechanism that uses small RNA molecules, such as small ...

An enzyme called RNA polymerase deciphers this code and converts ... Shedding light on how fundamental cellular mechanisms work in bacteria paves the way to developing new ways to fight bacterial ...

The goal of my research is to understand the mechanisms and structures of enzymes that perform and regulate essential nucleic acid transactions. My research integrates diverse experimental approaches ...

RNA cleavage can occur either: (i) by a transesterification mechanism that yields 2’,3’-cyclic-PO 4 and 5’-OH ends; or (ii) via a hydrolytic mechanism that leaves 3’-OH and 5’-PO 4 ends. RNA repair ...