The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
News Medical on MSN2d
Splicing twins: unravelling the secrets of the minor spliceosome complex
Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
AZoLifeSciences on MSN16h
Understanding the Complex Architecture of the Minor Spliceosome
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
News Medical8h
Evaluating influenza vaccine ingredients
The influenza A virus genome consists of eight segments of single-stranded, negative-sense viral RNA, which encode multiple ...
Nature2d
Biological sciences articles from across Nature Portfolio
Such screens genetically perturb many genes in parallel and use single-cell RNA sequencing to assess the transcriptomic effects. Now, an in vivo protocol facilitates screens in mouse brain ...
Nature4d
RNA articles from across Nature Portfolio
RNA (ribonucleic acid) is a nucleic acid polymer where the carbohydrate is ribose. RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is ...
eLife2d
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...