C&EN5d
Designer enzymes take a big step forward
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The EMBO Journal3d
Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Glioblastomas (GBM) are treated with high ...
Frontiers3d
Targeting the PI3K/AKT/mTOR pathway in lung cancer: mechanisms and therapeutic targeting
Figure 2. Schematic Representation of the PI3K/AKT/mTOR Pathway. This figure illustrates the PI3K/AKT/mTOR pathway involved in cell growth, protein synthesis, lipid biogenesis, and autophagy ...
eLife6d
Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
SMG1 specific inhibitor SMG1i11 (11j)[32] and KVS0001 were synthesized by Ascendex LLC (Pennsylvania, USA). The synthesis scheme for KVS0001 is located below. Emetine was obtained from Sigma Aldrich ...