Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex ... for both transcription and RNA replication and mutations that have ...

For SARS-CoV-2, two RNA sites ... dominant structures observed in the conformational landscapes. Long sequences promote the formation of unknotted stem-loops that contain an elongated AS1 of 12 base ...

Here, the knowledge relating to miRNAs’ relationships between host miRNAs and RNA viruses are discussed. Figure 1 The process of miRNA formation. The miRNA genes are transcribed for pri-miRNA by ...

Methods: Hematoxylin and Eosin staining was used to detect the placental structure ... RNA. Second strand cDNA synthesis was subsequently performed using DNA PolymeraseI and dNTP. Remaining overhangs ...

To cap the RNA product, m7G(5’)ppp(5’)G RNA Cap Structure Analog (New England Biolabs ... 10 μg of the purified RNA was then polyadenylated by 4U poly(A) polymerase (New England Biolabs) at 37°C for 1 ...

They say that change takes time. Well, that's not the case for RNA. The small biological molecule acts like a switchboard ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Another important discovery was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus to produce the correct ...