Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...
Having two copies of the MTHFR gene mutation may raise your risk for certain health conditions, though more research is needed. You may have the mutation and not find out unless you undergo ...
However, despite the availability of gene expression and epigenomic datasets, few variant-to-gene links have emerged. It is unclear whether these sparse results are due to limitations in available ...
In the late 2010s eight macaque monkeys were born at a laboratory in Shanghai. At first they seemed much like the other infants in the colony, but differences soon became obvious. They were much ...
Building a gene editor took months. With CRISPR even high-schoolers can get hold of editing systems in the time it takes to order RNA sequences online and have them shipped by FedEx. In a short ...
Jace, 6, was born with a rare and aggressive eye condition An experimental trial of gene therapy has helped four toddlers - born with one of the most severe forms of childhood blindness - gain ...
A new study links a particular gene to the ancient origins of spoken language, proposing that a protein variant found only in humans may have helped us communicate in a novel way. Speech allowed us to ...
Mice carrying a gene variant present in nearly every human on Earth — but not in extinct relatives including Neanderthals — produce more-complex chirps than normal rodents do 1. The finding ...
Next generation sequencing (NGS) confirmed the tumor was microsatellite stability (MSS), and a total of 6 gene mutations, TSC2, CREBBP, HIST1H3I, MAP2K4, SMAD4, and STK11 were detected. Additionally, ...
For a given gene in a given experimental condition ... group SMAD consisted of SMAD3, SMAD4, SMAD9; group AP-1 consisted of JUN, JUNB, JUND, JDP2, FOS, FOSB, FOSL1, FOSL2, BACH1, BACH2, BATF (note the ...
2015), the Gene Expression Omnibus (GEO ... might affect the apoptosis and proliferation of human colon cancer cells through SMAD family member 4 (SMAD4) and serve as a prognostic marker for colon ...