A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

Another important discovery was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus to produce the correct ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

Enzymes made of RNA are called "ribozymes." A group of researchers led by Professor Claudia Höbartner at the University of Würburg (JMU) has now uncovered the three-dimensional structure of a ...

Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700 032, India Academy of Scientific and Innovative Research (AcSIR), ...

Diacylglycerols (DAGs) are used for metabolic purposes and are tightly regulated secondary lipid messengers in eukaryotes. DAG subspecies with ... using anti GFP antibody. Structure of respective DAGs ...

Unlike previous reviews focused primarily on eukaryotes, this review aims to provide a comprehensive summary of recent knowledge about lysine lactylation in prokaryotes and eukaryotes. The current ...

Projects aimed at the exhaustive identification of RNAs, unbiased by genome annotations, have uncovered unexpected complexity of the transcriptome in eukaryotes. Several transcripts are generated ...

The biosynthesis of a translationally competent eukaryotic mRNA requires many events to be initiated by RNA polymerase II (Ref. 2). A 5′ 7-methylguanosine cap structure is incorporated co ...

The course focuses on current understanding of the structure and function of eukaryotic transcription factors. Topics covered are: promoters, RNA polymerase II, general transcription factors and ...