Human genetics provides clues to why DNA regulatory regions get 'loopy'
DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...
The EMBO Journal4d
PIF/harbinger transposon-derived protein promotes 7SL expression to enhance pathogen resistance
The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...
technologynetworks6d
Shared Mechanism Drives Enhancer Region Looping and Activation
RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...