Drs Ursula A. Matulonis and Panagiotis A. Konstantinopoulos discuss hormonal therapy updates and different ways to target and ...

Discover why male breast cancer cases are rising, learn essential warning signs most men miss, and understand new treatment options that could save lives.

Id., 2:36-38. “Tamoxifen is a selective estrogen receptor modulator that is used for the treatment of women with endocrine responsive breast cancer.” Id., 1:63-66. The ’334 patent also ...

In addition to its potent anti-estrogen effects ... proliferative effects compared with standard treatments, like tamoxifen.

As a complete estrogen receptor antagonist ... completion of adjuvant therapy without progression unless they'd had tamoxifen. And I think those features that we've enriched for, were carefully ...

Atossa Therapeutics, Inc. (Nasdaq: ATOS) (“Atossa” or the “Company”), a clinical-stage biopharmaceutical company dedicated to the prevention and treatment of breast cancer, today issued the following ...

Tamoxifen is a selective estrogen receptor modulator. It can be used to prevent breast cancer in humans and preclinical research has shown that it could reduce signs of muscular pathology in a mouse ...

Tamoxifen binds to ERs, preventing it from interacting with estrogen. This prevents the breast tumor cells from growing and multiplying. Increased expression of the HER2 protein is associated with ...

they designed and synthesized another clozapine PROTAC targeting the estrogen receptor alpha (ERα), which was shown to induce degradation of the ERα protein in MCF-7 breast cancer cells. Experiments ...