A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate ...

Interferon regulatory factor 3 (IRF3) is a key transcription factor in the type I interferon signaling. Its activation must be tightly controlled to efficiently activate innate immunity while avoiding ...

In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...

Casdatifan targets a transcription factor that binds with other proteins to switch off the body’s anti-inflammatory mechanisms, empowering genes that promote tumor growth in clear cell renal cell ...

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

Junevity, a biotechnology company on a mission to extend lifespan and healthspan by resetting cell damage from age-related ...

A recent study has revealed the molecular mechanisms behind the temperature-dependent and tissue-specific accumulation of ...

A new study reveals how the CaMYB80 transcription factor enhances cold tolerance in pepper plants, a crucial step toward ...

In a world where content is king, audiograms have emerged as a game-changing way to repurpose audio into engaging visual formats. These short, dynamic videos, often featuring audio waveforms, captions ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Environmental factors like stress and medication exposure during pregnancy can shape brain development, but the mechanisms ...