Mirikizumab showed superior maintenance efficacy over most treatments for ulcerative colitis (UC), according to a network ...
Recent reports have now implicated interleukin 12 and interleukin 23 ... The human monoclonal antibody ustekinumab blocks the biologic activity of IL-12 and IL-23 by inhibiting receptors of ...
The FDA's approval is grounded in an evidence totality and comprehensive data package, which includes outcomes from a study.
January started the year off strong, with several business updates, long-term clinical trial results on multiple biosimilars, ...
Activated macrophages engulf the microbiota and produce increased levels of interleukin-23 and interleukin-12 ... The monoclonal antibody ustekinumab can bind to the IL-12p40 subunit, interfering with ...
The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...