This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

Researchers investigated cerebral small vessel disease, a precursor to dementia, by analyzing data from thousands of ...

Ossification of the posterior longitudinal ligament (OPLL ... with ossified ligament tissues obtained from surgical procedures. Single-cell RNA sequencing (scRNA-seq) was performed to analyze ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

There is a considerable clinical need for alternatives to the autologous vein and artery tissues used for vascular reconstructive surgeries such as CABG, lower limb bypass, arteriovenous shunts ...

"Nutritional factors can impact brain health through inflammation, oxidative stress, vascular function ... depression occurs in about 50%. "A longitudinal analysis showed that 40% of older ...

Collagen diseases constitute a group of illnesses characterized by a variety of connective-tissue lesions with varying degrees of vascular involvement. 32 Autoimmune phenomena such as antinuclear ...

The myriad causes of compartment syndrome and the severe soft tissue findings that are associated ... infection, burns, or vascular injury, causes prolonged elevation of ITP.

DeGolier's research interests include smooth muscle physiology and pharmacology in vitro, peptide regulation of gastrointestinal, uterine, and vascular smooth ... constituents on isolated longitudinal ...