The NFL trade rumor mill never stops, and one San Francisco 49ers breakout rookie from the 2024 season got caught in the mix.

Just a year ago, the 49ers traded up to take Isaac Guerendo in Round 4. Now, he might not make their 53-man roster ...

That led PFSN to name second-year running back Isaac Guerendo as a player the 49ers could aim to deal after adding two rookies during the NFL draft. Via PFSN: The San Francisco 49ers can never ...

"The San Francisco 49ers can never resist an enticing mid-round running back prospect," Xie wrote. "Last year, Isaac Guerendo was the target, but he might already be old news. The Niners drafted ...

The 49ers need Jordan James to contribute right away because they can't use Christian McCaffrey the same way they used to.

Joe Williams (2017, fourth round), Trey Sermon (2021, third round) and Ty Davis-Price (2022, third round) were beat out by ...

"Good Morning Football" reacts to tight end George Kittle's new four-year contract with the San Francisco 49ers.

The San Francisco 49ers made a league-high 11 selections in the 2025 NFL Draft. General manager John Lynch and head coach ...