
Synaptonemal complex - Wikipedia
The synaptonemal complex (SC) is a protein structure that forms between homologous chromosomes (two pairs of sister chromatids) during meiosis and is thought to mediate synapsis and recombination during prophase I during meiosis in eukaryotes.
A molecular model for self-assembly of the synaptonemal complex protein ...
The synaptonemal complex (SC) is a supramolecular protein assembly that mediates homologous chromosome synapsis during meiosis. This zipper-like structure assembles in a continuous manner between homologous chromosome axes, enforcing a 100-nm ...
Synaptonemal Complex in Human Biology and Disease - PMC
The synaptonemal complex (SC) is a meiosis-specific multiprotein complex that forms between homologous chromosomes during prophase of meiosis I. Upon assembly, the SC mediates the synapses of the homologous chromosomes, leading to the formation of ...
Synaptonemal complex: Current Biology - Cell Press
Mar 8, 2021 · The synaptonemal complex (SC) is a meiosis-specific multiprotein complex that forms between homologous chromosomes during prophase of meiosis I. Once assembled, the SC mediates and maintains synapsis along the full length of each pair of homologous chromosomes.
The organization, regulation, and biological functions of the ...
The synaptonemal complex (SC) is a meiosis-specific proteinaceous macromolecular structure that assembles between paired homologous chromosomes during meiosis in various eukaryotes.
Dynamic molecular architecture of the synaptonemal complex
Jan 22, 2025 · Using a probabilistic mapping approach to analyze super-resolution image data, we detect changes in the organization of the synaptonemal complex in wild-type animals that coincide with crossover designation. We also found that …
Dynamic molecular architecture of the synaptonemal complex
Jan 22, 2025 · The synaptonemal complex (SC) plays essential roles in CO formation and patterning. This protein structure assembles between homologous chromosomes during meiotic prophase, mediating and stabilizing parallel alignment along their lengths .
Synaptonemal Complex Proteins: Specific Proteins of Meiotic
The review considers proteins of the synaptonemal complex (SC), a specific structure formed between homologous chromosomes in maturing germline cells during meiotic prophase I. The structure and functions are described for proteins that form ultrastructural SC elements in mammals, in yeast, and in higher plants.
Skp1 proteins are structural components of the synaptonemal complex …
Feb 14, 2024 · The synaptonemal complex (SC) is a zipper-like protein assembly that links homologous chromosomes to regulate recombination and segregation during meiosis. The SC has been notoriously refractory to in vitro reconstitution, thus leaving its molecular organization largely unknown.
The mammalian synaptonemal complex: protein components, …
Jul 15, 2012 · The synaptonemal complex (SC) is a proteinaceous structure of chromosome bivalents whose assembly is indispensable for the successful progression of the first meiotic division of sexually reproducing organisms. In this mini-review we will focus on recent progress dealing with the composition and ass …